Postoperative pain continues to be inadequately controlled. Therefore, opioid monotherapy should
no longer be viewed as an adequate strategy. This monograph discusses clinical
experience with a multimodal regimen incorporating IV acetaminophen.
Important Safety Information:
OFIRMEV® (acetaminophen) Injection is indicated for the management of mild to moderate pain; the management of moderate to severe pain with adjunctive opioid analgesics; and the reduction of fever.
|WARNING: RISK OF MEDICATION ERRORS AND HEPATOTOXICITY
Take care when prescribing, preparing, and administering OFIRMEV injection to avoid dosing errors which could result in accidental overdose and death.
OFIRMEV contains acetaminophen. Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed the recommended maximum daily limits, and often involve more than one acetaminophen-containing product.
Please see Full Prescribing Information, Including complete Boxed Warning.