Postoperative pain continues to be inadequately controlled. Therefore, opioid monotherapy should no longer be viewed as an adequate strategy. This monograph discusses clinical experience with a multimodal regimen incorporating IV acetaminophen.

OFIRMEV® (acetaminophen) Injection is indicated for the management of mild to moderate pain; the management of moderate to severe pain with adjunctive opioid analgesics; and the reduction of fever.

Important Safety Information:

Take care when prescribing, preparing, and administering OFIRMEV injection to avoid dosing errors which could result in accidental overdose and death.

OFIRMEV contains acetaminophen. Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed the recommended maximum daily limits, and often involve more than one acetaminophen-containing product.

Please see Full Prescribing Information, Including complete Boxed Warning.

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The Role of Multimodal Analgesia in General Surgery: A Review of Clinical Data and Case-Based Presentations Featuring OFIRMEV® (acetaminophen) Injection

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