Originally published by our sister publication Infectious Disease Special Edition
By Laurie Fickman
Omadacycline (Nuzyra, Paratek) may help prevent Clostridioides difficile infections, which are responsible for nearly 500,000 infections annually in the United States (J Infect Dis 2023 Dec 5. doi:10.1093/infdis/jiad537).
Omadacycline had demonstrated a low likelihood of causing C. difficile in clinical trials, but no one understood why. In a small phase 1 human clinical trial, Kevin Garey,