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OCTOBER 7, 2019

Early Results Hint at Link Between Neuroinflammation and Cognition

By Michael Vlessides
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Thomas Bunning, BS

Montreal—Early results from an ongoing trial suggest there may be a link between neuroinflammation and postoperative delirium/cognitive dysfunction in older people undergoing surgery.

According to interim findings from the study, patients experiencing postoperative cognitive dysfunction had demonstrable alterations in both their cerebrospinal fluid (CSF) monocyte/lymphocyte ratio and CSF monocyte MCP-1 receptor expression. The difference persisted at