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NOVEMBER 8, 2018

Finding the Drivers of Locoregional Recurrence Of Breast Cancer

Importance of Tumor Burden Overestimated

By Monica J. Smith

Orlando, Fla.—Despite the complex phenomenon of increasing rates of bilateral and contralateral prophylactic mastectomy for breast cancer, data have emerged in the past couple of decades showing that bigger surgery doesn’t necessarily reduce the risk for locoregional recurrence. There was a time, though, when more aggressive surgery seemed reasonable: The watershed trials that found no difference between mastectomy and breast-conserving surgery also described