Originally published by our sister publication Clinical Oncology News
Chemotherapy before and after surgery for locally advanced esophageal adenocarcinoma—the FLOT protocol—improved survival relative to chemoradiotherapy before surgery, which is known as the CROSS protocol, according to results from a randomized multicenter trial.
Both the FLOT and CROSS protocols have been standard-of-care guideline-recommended approaches to locally advanced, resectable esophageal cancer, but it was