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NOVEMBER 27, 2017

Study Questions Value of Universal Lynch Testing for Colorectal Patients

By Caroline Helwick

Many countries, including the United States, advocate screening all patients with colorectal cancer for Lynch syndrome. But a pair of studies raises questions about the utility of that strategy—at least in part.

One study, from the Netherlands, found that universal screening for Lynch syndrome using immunohistochemistry (IHC) staining does not appear worthwhile in people with CRC. Meanwhile, a second study showed that the screening test works as intended in women with