‘Life isn’t a matter of milestones, but of moments.’—Rose Kennedy

The 2022 Clinical Congress of the American College of Surgeons not only is celebrated for the initial in-person gathering following the ebbing of the COVID-19 pandemic, but is also notable as the culmination of a year-long celebration of the establishment of the cancer initiatives of the ACS that first began in 1922. In 1921, the ACS Board of Regents authorized the