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APRIL 30, 2018

Preoperative Chemotherapy Improves Outcomes in Node-Negative Gastric Cancer

By Kate O’Rourke

In patients with gastric cancer who receive chemotherapy before gastrectomy, resulting in downstaged disease (cN+ ypN0), overall survival is similar to that of patients with natural node-negative disease (cN0 ypN0), according to a recent study. The report is the first to shine a light on this clinical question.

“In this retrospective cohort study, ypN status is a significant prognostic factor for overall survival [OS]. However, there is no survival difference between