By Ted Bosworth
Nissen fundoplication is “significantly superior” to medical therapy for patients with gastroesophageal reflux disease whose heartburn fails to improve with proton pump inhibitors, according to a new multicenter trial from the Veterans Administration.
Previous reports show that up to 40% of patients with GERD symptoms do not obtain adequate control from PPIs, which are regarded as the first-line medical treatment for the condition. For the majority of these patients,