By Ted Bosworth
Delivering macronutrients to the distant small intestine may prove to be a noninvasive treatment for obesity, Dutch researchers have found. In a crossover design, food intake was significantly reduced after ingestion of encapsulated micronutrients that reached the ileum when compared with a similar product that did not.
The researchers called their study a “proof of concept” that the ileal brake—a phenomenon in which undigested macronutrients reaching the distal